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In trials where semaglutide tablets was added on to metformin and/or sulfonylurea, basal insulin alone, or metformin in combination with basal insulin in patients with moderate renal impairment, severe hypoglycemia was not reported in any of the patients in the trial

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Hwang, S

Cagrilintide showed the potency

While the clinical translation is still in its early days, the mechanistic rationale is compelling, and the preclinical evidence is impressive

And we believe there is a place for mandatory serious adverse events reporting related to these substances. What could the future look like